Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5903094 | Metabolism | 2016 | 11 Pages |
Abstract
We demonstrated for the first time that a DPP-4 inhibitor can substantially suppress plaque formation in coronary arteries with a marked reduction in macrophage accumulation likely via its anti-inflammatory properties.
Keywords
TNFMDAEVGGIPTBARSGAPDHQ-RT-PCRGLPMCPDPPVLDLHDLhigh-density lipoproteinivGTTPAF-AHAtherosclerosisintravenous glucose tolerance testenzyme linked immunosorbent assayapoapolipoproteinsmooth muscle actininterleukinanalysis of varianceANOVAELISArabbitsstandard error of the meanSMAdipeptidyl peptidaseDipeptidyl peptidase-4platelet-activating factor acetylhydrolasetumor necrosis factorcardiovascularvery-low-density lipoproteinLow-density lipoproteinLDLmalondialdehydeMacrophageSEMthiobarbituric acid reactive substancesElastic Van Giesonquantitative reverse transcription-polymerase chain reactionmonocyte chemoattractant proteinglucagon-like peptidechylomicronsliquid chromatography–tandem mass spectrometryHPLChigh-performance liquid chromatographycholesterolglyceraldehyde 3-phosphate dehydrogenaseglucose-dependent insulinotropic polypeptide
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Authors
Tsutomu Hirano, Satoko Yamashita, Masaki Takahashi, Hiroyuki Hashimoto, Yusaku Mori, Moritaka Goto,