| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5903117 | Metabolism | 2014 | 17 Pages |
Abstract
FFAR1 can mediate PIO suppression of β-cell lipoapoptosis through anti-oxidative stress, which may be related to the activation of the PLCγ-ERK1/2-PPARγ pathway.
Keywords
PPARγGPR40PLCγFFAsPDX-1GSISIP3G protein-coupled receptor 40DCFH-DAqRT-PCRNADPHFFAR1GLUT-2ERK1/2MOIpIOROSFree fatty acidsGlucose-stimulated insulin secretionOxidative stressβ cellLipoapoptosisnicotinamide adenine dinucleotide phosphatePalmitic acidmultiplicity of infectionnegative controlextracellular signal-regulated kinase 1/2PioglitazoneFree fatty acid receptor 1Peroxisome proliferator activated receptor gamma
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Authors
Ximei Shen, Liyong Yang, Sunjie Yan, Wenfeng Wei, Liyu Liang, Huanhuan Zheng, Xiuhui Cai,