| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5903248 | Metabolism | 2015 | 12 Pages |
Abstract
DHEA prevents LA-induced endothelial senescence by restoring autophagy and autophagic flux through JNK activation.
Keywords
AMPKSA-β-galATGPAI-1DHEA-SdehydroepiandrosteronePRBeNOSERKICAM-1mTORC1VLDLFFAIDLGFP-LC3PI3KSQSTM1Autophagy related genessequestosome 1JnkDHEAFBSAMP-activated protein kinasec-Jun N-terminal kinaseDMSOMAPKSmall interfering RNAROSsiRNAAtherosclerosisAutophagyLinoleic acidFree fatty acidHAECcardiovascular diseaseANOVAone-way analysis of varianceDimethyl sulfoxideCVDAgingfetal bovine serumEndothelial cellshuman aortic endothelial cellsendothelial nitric oxide synthasedehydroepiandrosterone sulfatephosphatidylinositide 3-kinasesvery low-density lipoproteinIntermediate-density lipoprotein Low-density lipoproteinLDLretinoblastoma gene productType 1 plasminogen activator inhibitorIntercellular adhesion molecule 1Nitric oxideMammalian target of rapamycin complex 1mitogen-activated protein kinaseextracellular signal-regulated kinaseReactive oxygen species
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Authors
Min Jung Lee, Eun Hee Kim, Sang Ah. Lee, Yu Mi Kang, Chang Hee Jung, Hae Kyeong Yoon, So Mi Seol, Yoo La Lee, Woo Je Lee, Joong-Yeol Park,