Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population

Article ID	Journal	Published Year	Pages	File Type
5903316	Metabolism	2015	9 Pages	PDF

Abstract

This study presents evidence of novel genomic regions and gene-diet interactions that may contribute to the pathophysiology of obesity-related traits among Yup'ik people.

Keywords

Nitrogen stable isotope ratio VLDL HDL RBC δ15N n-3 PUFA N-3 fatty acids Omega-3 polyunsaturated fatty acids Alaska native LOD یا Limit of detection body mass index BMI logarithm of the odds high density lipoprotein very low density lipoprotein low density lipoprotein LDL Obesity Genome-wide association study GWAS Single nucleotide polymorphism Linkage SNP red blood cell

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology

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Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population

Authors

Laura Kelly Vaughan, Howard W. Wiener, Stella Aslibekyan, David B. Allison, Peter J. Havel, Kimber L. Stanhope, Diane M. O'Brien, Scarlett E. Hopkins, Dominick J. Lemas, Bert B. Boyer, Hemant K. Tiwari,