| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5903335 | Metabolism | 2014 | 53 Pages |
Abstract
Finally, as the potential of thermogenic adipocyte activation as a therapeutic approach for the treatment of obesity and associated metabolic diseases becomes evident, we highlight goals and challenges for current research on the road to clinical translation.
Keywords
PRDM16PGC1α18FDGPDGFRαFGF21RB1NEFAPGI2PKGDNPbeige/brite adipocytesp38pKaBATPPARγmRNAcPGI2PPARγ coactivator 1αEHMT1cGMP2,4-Dinitrophenolc/ebpβcAMPUcp1Adenosine TriphosphateATPCyclic adenosine monophosphateAdipogenesisNon-esterified fatty acidMRIWAT, White adipose tissuebrown adipose tissueThermogenesisMagnetic resonance imagingcomputed tomographyPositron emission tomographyretinoblastoma 1messenger ribonucleic acidbody mass indexBMIfibroblast growth factor 21BMPObesitycyclic guanosine monophosphatenoradrenalinEnergy expenditurePETCCAAT/enhancer binding protein βBone morphogenetic proteinprotein kinase Aprotein kinase Gprostacyclinprostaglandinnatriuretic peptidesWATcarbaprostacyclinplatelet-derived growth factor receptor α
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Authors
Mauricio Berriel Diaz, Stephan Herzig, Alexandros Vegiopoulos,