| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5903376 | Metabolism | 2014 | 29 Pages |
Abstract
Both obesity and T2D are associated with an altered epigenetic signature of the immune system in a cell type-specific manner. These changes could contribute to the altered immune functions associated with obesity and insulin resistance.
Keywords
5meCD-PBSPBMCsT2DFBSPFAMFI5mdCHOMA-IRnatural killer5-MethylcytosineBSALC-MS/MSbovine serum albuminHomeostasis model assessmentMetabolic diseasesEpigenetic changesType 2 diabetesfetal bovine serumperipheral blood mononuclear cellsbody mass indexBMImedian fluorescence intensityDulbecco's phosphate-buffered salineFlow cytometryLeukocytesparaformaldehydeliquid chromatography tandem mass spectrometry
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Authors
David Simar, Soetkin Versteyhe, Ida Donkin, Jia Liu, Luke Hesson, Vibe Nylander, Anna Fossum, Romain Barrès,