| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5903405 | Metabolism | 2015 | 9 Pages |
Abstract
These results suggest that the addition of MCT to PFO formulations may decrease the host response to inflammatory challenge, which may pose potential for optimized PN formulations. Inclusion of MCT in lipid emulsions given with PN formulations may be of use in therapeutic interventions for disease states resulting from chronic inflammation.
Keywords
DHLAEFADPFOEFAMCTALAPNALDHCOIL-6LPSArachidonic aciddocosahexaenoic acidLinoleic acidalpha linolenic acidEssential fatty acidPolyunsaturated fatty acidPUFAinflammationinterleukin 6Parenteral nutrition-associated liver diseaseMedium-chain triglyceridesParenteral nutritiontumor necrosis factor alphaintraperitonealARADHAdihomo-gamma-linolenic acidFish oilhydrogenated coconut oilTNF-αlipopolysaccharideC-reactive proteinCRPEssential fatty acid deficiency
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Authors
Sarah J. Carlson, Prathima Nandivada, Melissa I. Chang, Paul D. Mitchell, Alison O'Loughlin, Eileen Cowan, Kathleen M. Gura, Vania Nose, Bruce R. Bistrian, Mark Puder,