| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5903409 | Metabolism | 2015 | 22 Pages |
Abstract
Methionine restriction improves glucose and lipid homeostasis; however, adding hepatic PTP1B inhibition to MR is unlikely to yield any additional protective effects.
Keywords
PIP3HprtNAFLDSHP2GSHPTTmTORC1PKBp70S6KPTP1Bp70 ribosomal S6 kinasepyruvate tolerance testinsulinDiabetesnon-alcoholic fatty liver diseasephosphatidylinositol (3,4,5)-trisphosphateMethionine restrictionmechanistic target of rapamycin complex 1Phosphatase and tensin homologuehypoxanthine-guanine phosphoribosyltransferaseRibosomal protein S6Protein tyrosine phosphatase 1Bprotein kinase BPtenLiverGlutathioneGlucoseinsulin receptor
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Authors
Emma Katherine Lees, Elzbieta Krol, Kirsty Shearer, Nimesh Mody, Thomas W Gettys, Mirela Delibegovic,