A de novo 4.4-Mb microdeletion in 2p24.3 → p24.2 in a girl with bilateral hearing impairment, microcephaly, digit abnormalities and Feingold syndrome

► We report a girl with Feingold syndrome and a 4.4-Mb deletion in 2p24.3 → p24.2. ► Phenotype includes hearing loss, microcephaly, facial dysmorphisms and digit defects. ► Genotype includes a microdeletion encompassing FAM84A, NBAS, DDX1, MYCNOS and MYCN. ► Haploinsufficiency of MYCN is responsible for Feingold syndrome. ► Hearing loss, microcephaly and digit defects should suggest Feingold syndrome.