Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5905393 | Gene | 2015 | 5 Pages |
Abstract
In our cohort, approximately 6% of cases diagnosed as T1DM were in fact patients with Wolfram syndrome. WFS1 mutations were identified in 4 out of 5 individuals (80%) fulfilling clinical criteria for WS. Clinical and genetic analyses of large cohorts of T1DM patients from different ethnic origins would help to better estimate the occurrence of WS and will lead to a better management of such patients.
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Genetics
Authors
Maria E. Blanco-Aguirre, David Rivera-De la Parra, Hugo Tapia-Garcia, Johanna Gonzalez-Rodriguez, Daniela Welskin, Maria Estela Arroyo-Yllanes, Irineo Escudero, Jorge A. Nuñez-Hernandez, Patricia Medina-Bravo, Juan C. Zenteno,