Article ID Journal Published Year Pages File Type
5906210 Gene 2013 36 Pages PDF
Abstract
In this article the special emphasis is to discuss the strategies of regulation of gene expression by endogenous stimuli. Particularly, the hypoxia- or miRNA-regulated vectors offer the possibilities of tight but, at the same time, condition-dependent and cell-specific expression. Such means have been already tested in certain pathophysiological conditions. This creates the chance for the translational approaches required for development of effective treatments of so far incurable diseases.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics
Authors
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