Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5906301 | Gene | 2013 | 11 Pages |
Abstract
Our results define a miRNA signature characterizing the osteogenic differentiation of MSCs and provide evidence for the involvement of miR-31 in the regulation of the bone-specific transcription factor Osterix.
Keywords
NFATc1AP-1Oct4Sox2HTRCOL1A1collagen, type I, alpha 1SRY (sex determining region Y)-box 9MD1WntSp7RFUBglapmm2TGF-βSRY (sex determining region Y)-Box 2Telomerase RNA componentKLF4MSCSox9FBSFGFRUNX2GAPDHATF43′ untranslated region3′UTRTCF/LEFALPAlkaline phosphataseOsteogenesisfetal bovine serumMesenchymal stem cellsTranscription factorrunt related transcription factor 2Krüppel-like factor 4fibroblast growth factoroctamer-binding transcription factor 4activating transcription factor 4BMPMicroRNAMiRNARelative Fluorescence Unitsactivator protein 1Bone morphogenetic proteinTwistglyceraldehyde-3-phosphate dehydrogenase
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Authors
Serena Rubina Baglìo, Valentina Devescovi, Donatella Granchi, Nicola Baldini,