Identifying differentially spliced genes from two groups of RNA-seq samples

Article ID	Journal	Published Year	Pages	File Type
5906658	Gene	2013	7 Pages	PDF

Abstract

âº Exon-based method to detect differentially spliced genes in two groups of samples. âº An NB-statistic with the negative binomial model to detect differential splicing. âº No need for known isoform structure, and can detect new alternative splicing events. âº A new route to quantitatively study alternative splicing in an exon-centric manner.

Keywords

RNA-seq DSG IPV RPKM Differential splicing reads per kilobase per million reads Alternative splicing Negative binomial Negative binomial model

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Genetics

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Identifying differentially spliced genes from two groups of RNA-seq samples

Authors

Weichen Wang, Zhiyi Qin, Zhixing Feng, Xi Wang, Xuegong Zhang,