Current evidence on the relationship between five polymorphisms in the matrix metalloproteinases (MMP) gene and lung cancer risk: A meta-analysis

Article ID	Journal	Published Year	Pages	File Type
5906835	Gene	2013	7 Pages	PDF

Abstract

MMP1-1607 1G/2G polymorphism increased lung cancer risk in Asians. It was also found thatMMP2-1306 C/T polymorphism decreased lung cancer risk in Asians, while MMP9-1562 C/T polymorphism decreased lung cancer risk in Caucasians. No significant difference was found in any genotype of MMP2-735 C/T and MMP3-1171 5A/6A. Further studies with larger sample sizes should be carried out.

Keywords

ECM MMP PCC HCC Risk Not available PCR-RFLP Lung cancer confidence interval Meta-analysis Extracellular matrix matrix metalloproteinase Matrix metalloproteinases (MMPs)MicroRNA MiRNA odds ratio Polymorphism polymerase chain reaction-restriction fragment length polymorphism Single nucleotide polymorphism SNP

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Genetics

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Current evidence on the relationship between five polymorphisms in the matrix metalloproteinases (MMP) gene and lung cancer risk: A meta-analysis

Authors

Chaoliang Hu, Jianmiao Wang, Yuzhu Xu, Xiaochen Li, Huilong Chen, Hansvin Bunjhoo, Weining Xiong, Yongjian Xu, Jianping Zhao,