| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5907021 | Gene | 2012 | 7 Pages |
Abstract
⺠We studied a Chinese family with inherited non-syndromic dental disorders. ⺠The clinical manifestations were not fully met in any classification subtypes. ⺠A novel gene mutation of G to A transversion in exon 4 of the DSPP gene was found. ⺠The presence of symptom heterogeneity is possible. ⺠Lack of close correlation between the subtype and the molecular defect exists.
Keywords
Col1a2Dentin phosphoproteinAMBNDLX3collagen type I alpha 2ENAMCollagen type I alpha 1AMELdentin dysplasiadentinogenesis imperfectaDGIDSPPamelogenesis imperfectaKLK4COL1A1DSPEGFDPPcentiMorganTGFβFGFKallikreinAsparagineAspartic acidAmeloblastinAmelogeninTransforming growth factor βdentin sialophosphoproteinepidermal growth factorFibroblast Growth FactorsMatrix metalloproteinase-20BMPEnamelinpolymerase chain reactionPCRbone morphogenetic proteins
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Genetics
Authors
Li Li, Yi Shu, Beiyan Lou, Hongkun Wu,