| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5907052 | Gene | 2013 | 6 Pages |
Abstract
⺠TagSNPs covered CRP gene, CRPP1 gene and 40 kb upstream were assessed for HT. ⺠SNPs rs876537 and rs10737175 of CRP gene had major effect on hypertension. ⺠Haplotype T-T structured of rs6677719 and rs10737175 had joint effect on HT. ⺠Age and sex might modify genetic effect of CRP gene on HT. ⺠rs10737175, rs2808630 and rs876537 are positively associated with BP elevation.
Keywords
DBPET-1HDL-ChsCRPCHBLDL-CHWESPSSMAFGLMSBPSNPsHigh sensitive CRPTFBSTagSNPsχ2EDTAProbabilityethylenediamine tetraacetic acidendothelin 1TriglyceridesHardy–Weinberg equilibriumStatistical Product and Service SolutionsPCR-RFLPbody mass indexBMILinkage disequilibriumconfidence intervalminor allele frequencyHypertensiondiastolic blood pressuresystolic blood pressureGeneral linear modelAssociation studygenome wide association studyGWASodds ratioNitric oxideC-reactive proteinCRPSingle nucleotide polymorphismsChi-squaretotal cholesterolhigh density lipoprotein cholesterollow density lipoprotein cholesterolGluGlucose
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Authors
Yanping Zhao, Hairu Wang, Sijun Liu, Xianghai Zhao, Yanchun Chen, Yichun Yang, Wen Wang, Yiming Wu, Aiqin Chen, Junming Tang, Yingshui Yao, Yun Li, Jinfeng Chen, Chong Shen, Song Yang,