Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5907074 | Gene | 2013 | 6 Pages |
Abstract
⺠Functional genetic differences in GST enzymes among human populations were analyzed. ⺠Ethnicity strongly affects the genetic variability of GST enzymes. ⺠Functional GST variants showed differences according to the population origin. ⺠These ethnic differences may influence disease risk or response to drugs.
Keywords
TSIHan Chinese in Beijing, ChinagstoGIHYRIJapanese in Tokyo, JapanGstAGSTTMAPEGJPTCNVsGSTMGSTPCHBCEUCHDGSTsASWIL-1βLOFMKKChi-square testEthiopiaLoss-of-functionEcuadorItalyInterleukin-1βPopulation demographyCopy number variantsLinkage disequilibriumPharmacogeneticsMEXGenetic polymorphismglutathione S-transferases
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Authors
Renato Polimanti, Cinzia Carboni, Ilenia Baesso, Sara Piacentini, Andrea Iorio, Gian Franco De Stefano, Maria Fuciarelli,