| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5907089 | Gene | 2013 | 9 Pages |
Abstract
⺠NHLH2 is a bHLH transcription factor that controls body weight and fertility. ⺠A 3â²UTR and a coding region SNP both reduce functional NHLH2 protein levels. ⺠The 3â²UTR SNP affects RNA secondary structure and mRNA stability. ⺠The basic domain SNP modifies the protein helical structure. ⺠Rare SNPs in NHLH2 may contribute to body weight or fertility phenotypes in humans.
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Authors
Numan AL_Rayyan, Umesh D. Wankhade, Korie Bush, Deborah J. Good,