Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5907107 | Gene | 2012 | 6 Pages |
Abstract
⺠CHO cells were engineered to carry a single human chromosome 11. ⺠Replication timing program at an R/G boundary was maintained in the CHO(h11) cells. ⺠Replication timing at the centromere was also similar to the original fibroblasts. ⺠The 11q telomere showed abnormally early replication in CHO(h11) cells. ⺠The telomere region may have a specific mechanism for regulating replication timing.
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Authors
Yoshihisa Watanabe, Yasuhiro Kazuki, Mitsuo Oshimura, Toshimichi Ikemura, Masato Maekawa,