Article ID Journal Published Year Pages File Type
5907107 Gene 2012 6 Pages PDF
Abstract
► CHO cells were engineered to carry a single human chromosome 11. ► Replication timing program at an R/G boundary was maintained in the CHO(h11) cells. ► Replication timing at the centromere was also similar to the original fibroblasts. ► The 11q telomere showed abnormally early replication in CHO(h11) cells. ► The telomere region may have a specific mechanism for regulating replication timing.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics
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