| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5907178 | Gene | 2012 | 7 Pages |
Abstract
⺠Pioneer report of IRS-1 and PPARγ gene association with PCOS among Indian women. ⺠Polymorphisms identified and analysed in 250 PCOS and 299 controls. ⺠IRS-1 polymorphic alleles had a similar distribution between cases and controls. ⺠PPAR γ variant alleles were significantly more in the controls than the PCOS cases. ⺠Haplotypes indicate protective gene role against specific PCOS sub-phenotypes.
Keywords
PPAR-γHWPTZDWHRESHREHDLRBSIRS-1ASRMT2DMINSRPCOSRandom blood sugarDNAdeoxyribose nucleic acidAmerican Society for Reproductive Medicineinsulin receptor substrate-1thiazolidinedionesstandard errortype-2 diabetes mellitusPolycystic ovary syndromebody mass indexBMILinkage disequilibriumconfidence intervalhigh density lipoproteinlow density lipoproteinLDLWaist hip ratioodds ratiofollicle stimulating hormoneluteinizing hormoneFSHpolymerase chain reactionPCRPolymorphismSingle nucleotide polymorphismSNPinsulin receptorPeroxisome proliferator-activated receptor-γ
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Authors
Shilpi Dasgupta, Pisapati Sirisha, Kudugunti Neelaveni, Katragadda Anuradha, Godi Sudhakar, B. Mohan Reddy,