Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5907275 | Gene | 2012 | 7 Pages |
Abstract
⺠We present a bioinformatic approach to identify genes associated with drug toxicity. ⺠Twist - to identify genes affected by drugs and expressed in toxicity related tissue. ⺠Genetic variants in these genes were genotyped in 94 cancer patients. ⺠Variants in ABCA1 and ATM were associated with paclitaxel/carboplatin toxicity.
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Genetics
Authors
Johanna Hasmats, Ilya Kupershmidt, Cristina RodrÃguez-Antona, Qiaojuan Jane Su, Muhammad Suleman Khan, Carlos Jara, Xabier Mielgo, Joakim Lundeberg, Henrik Green,