Article ID Journal Published Year Pages File Type
5907275 Gene 2012 7 Pages PDF
Abstract
► We present a bioinformatic approach to identify genes associated with drug toxicity. ► Twist - to identify genes affected by drugs and expressed in toxicity related tissue. ► Genetic variants in these genes were genotyped in 94 cancer patients. ► Variants in ABCA1 and ATM were associated with paclitaxel/carboplatin toxicity.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics
Authors
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