| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5907287 | Gene | 2012 | 11 Pages |
Abstract
⺠Two C. elegans coq-3 null mutants lack coenzyme Q but have distinct phenotypes. ⺠One null coq-3 mutant shows limited fertility, while the other is sterile. ⺠Unlike clk-1 mutants, neither coq-3 mutant is rescued with dietary Q supplements. ⺠coq-3 mutants rescued for de novo Q synthesis are as fertile as wild-type worms. ⺠Augmenting de novo synthesis of Q is more effective than dietary therapies with Q.
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Authors
Fernando Gomez, Ryoichi Saiki, Randall Chin, Chandra Srinivasan, Catherine F. Clarke,