Identification of candidate genes involved in clinical variability among Tunisian patients with Î²-thalassemia

Article ID	Journal	Published Year	Pages	File Type
5907306	Gene	2012	7 Pages	PDF

Abstract

âº Î²-thalassemic patients were divided into Î²-thalassemia major (TM) and intermedia (TI). âº STR were studied in search of a new explanation for phenotypic variability. âº Comparison has shown for one STR, one specific allele to TM patients âº Comparison has shown for two STR, two specific alleles to TI patients âº STR identified are probably linked to genes able to act on Î²-thalassemia expression.

Keywords

MCC STR PND β-thalassemia intermedia β-thalassemia β-thalassemia major Short tandem repeats Prenatal diagnosis Hémoglobine