| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5907376 | Gene | 2012 | 9 Pages |
Abstract
⺠Upon feeding elongation and desaturation take place for fatty acid synthesis (FAS). ⺠After feeding, dietary lipids (DL) suppress saturated and monounsaturated synthesis. ⺠Elovl7 may be downregulated by insulin and this effect increases by DL. ⺠Regulation of elongases may have a Srebf-1c-independent pathway upon feeding. ⺠Upregulation by feeding of FAS does not compensate for the inhibitory effect of DL.
Keywords
EPAFADS1elongasesLC-PUFAsELOVLFADS2HLDChREBPSREsDEPCALAALDα-linolenic acidArachidonic acidEicosapentaenoic aciddocosahexaenoic acidFatty acid desaturase 1Linoleic acidfatty acid desaturase 2fatty acid synthaseFatty acidsLong-chain polyunsaturated fatty acidsinsulinDesaturasesDHAdiethylpyrocarbonateFasncarbohydrate-responsive element-binding protein
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Authors
Maricela RodrÃguez-Cruz, Raúl Sánchez González, Apolos M. Sánchez GarcÃa, Mardia Lòpez-Alarcòn,