Article ID Journal Published Year Pages File Type
5907467 Gene 2012 9 Pages PDF
Abstract
► We examine gene expression profile of MSC in an experimental inflammatory condition. ► STAT2 is highly upregulated when MSC is stimulated by IFN-γ and TNF-α. ► STAT2 knockdown inhibits MSC-mediated T-cell suppression. ► STAT2 is found to be involved in the immunosuppression of MSC.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics
Authors
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