| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5907469 | Gene | 2012 | 7 Pages |
Abstract
⺠Peloruside A, a microtubule stabilising agent, inhibits yeast cell division. ⺠Paclitaxel, another stabilising agent, does not significantly inhibit yeast growth. ⺠Deletion of the mitotic checkpoint gene MAD2 increases sensitivity to peloruside. ⺠Using chemical genetics, genetic interactions with peloruside can be identified. ⺠Peloruside interacts with cell cycle genes, mitosis, RNA splicing, and trafficking.
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Authors
Anja Wilmes, Reem Hanna, Rosemary W. Heathcott, Peter T. Northcote, Paul H. Atkinson, David S. Bellows, John H. Miller,