A regulatory cascade of three transcription factors in a single specific neuron, DVC, in Caenorhabditis elegans

Article ID	Journal	Published Year	Pages	File Type
5907553	Gene	2012	12 Pages	PDF

Abstract

âº The C. elegans homeobox gene ceh-63 is expressed in a single interneuron, DVC. âº Although a highly conserved gene, a ceh-63 null mutant had no major phenotype. âº A transcription factor regulatory cascade operating in DVC was defined.

Keywords

IPTG ChR2 channelrhodopsin-2 NGM DAPI Y2H YFP GFP ORF DIC FITC Neural gene expression NTP 4′,6-diamidino-2-phenylindole DNA RNA interference RNAi EST deoxyribonucleic acid RNA ribonucleic acid isopropyl β-D-1-thiogalactopyranoside analysis of variance ANOVA nucleotide triphosphate Expressed Sequence Tag base pairs DNA binding domain activation domain nematode growth media Hour Transcription factor Homeodomain transcription factors fluorescein isothiocyanate open reading frame Yeast two hybrid UTR یا untranslated regions untranslated region polymerase chain reaction PCR yellow fluorescent protein green fluorescent protein Caenorhabditis elegans differential interference contrast