| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 590779 | Advances in Colloid and Interface Science | 2013 | 15 Pages |
•Importance of gold compounds in biomedical applications is discussed.•Surface modification of gold NPs widens their applicability in biomedical therapy.•Gold NPs bound with biological moieties have been used profoundly in biosensors.•Use in clinical applications like imaging and therapeutic radio sensitizers
In the medical field, majority of the active ingredients exists in the form of solid particle (90% of all medicines). Nanotechnology had grabbed the attention of many scientists working in different aspects and gave them a vivid imagination in order to utilize the nanotechnology in an innovative way according to their needs. One of the major applications of nanotechnology is drug delivery through nanoparticles which is on boom for the researchers and gives a challenging environment for the researchers. Among them upcoming challenge is the use of inorganic nanoparticles for the drug delivery and related aspects. There is growing interests in usage of inorganic nanoparticles in medicine due to their size, and unique physical properties that make them different from other nanoparticulate systems. This review will lay special emphasis on the uniqueness of inorganic nanoparticles especially gold nanoparticles as a drug delivery vehicle and moreover will present a wide spread scenario of gold nanoparticles that has been used for treatment of life threatening diseases like cancer.
Graphical abstractNanomaterials have recently attracted strong interest from the scientific community all over the world not only as budding drug delivery vehicles, but also as diagnostic tools, as a radio contrast agent in cancer therapy and as biomarkers in molecular deep tissue imaging techniques. This review mainly focuses on gold nanoparticles and discusses the role of gold nanoparticle in drug delivery, including their synthesis, chemical modifications, properties and their usage as biomarkers in the pharmaceutical field. The review focuses on the recent contribution of gold nanoparticles in the medical field.Figure optionsDownload full-size imageDownload as PowerPoint slide
