| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5907905 | Genomics | 2012 | 10 Pages |
Abstract
⺠Two variants of a phylogenetically conserved regulatory module in NGN3 (NEUROG3) target genes. ⺠Both variants consisted of transcription factors implicated in pancreas development. ⺠An additional factor present only into the module of down-regulated by NGN3 genes. ⺠Alternative protein complexes formed through protein-protein interactions. ⺠Regulatory network of the analyzed genes leading into β-cells' differentiation.
Keywords
RGS4CDC42CTNNB1ESCsNeuroD1TFBSPdx1WISP1LEF1TSSPard3CREBBPPax4Regulator of G-protein signaling 4lymphoid enhancer-binding factor 1VCLISL LIM homeobox 1SPCHDAC1RMSDVinculinPwMSCTGFCSSIPAMSSTFsDcxPancreatic and duodenal homeobox 1isl1NVTIngenuity Pathway AnalysisdoublecortinMolecular dynamicstranscription start siteRoot Mean Square DeviationsTranscription factor binding sitesEmbryonic stem cellsSimple Point Chargehepatocyte nuclear factor 1Transcription factorsConnective tissue growth factorgeneralized BornNeurogenin3histone deacetylase 1CREB binding protein
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Authors
Maria Kapasa, Dimitrios Vlachakis, Myrto Kostadima, Georgia Sotiropoulou, Sophia Kossida,