Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
590946 | Advances in Colloid and Interface Science | 2011 | 10 Pages |
Abstract
Tropoelastin coacervation in vivo is thought to mainly involve the central hydrophobic domains. In addition, cell-surface glycosaminoglycans and microfibrillar proteins may regulate the process. Coacervation is essential for progression to downstream elastogenic stages, and impairment of the process can result in elastin haploinsufficiency disorders such as supravalvular aortic stenosis.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Giselle C. Yeo, Fred W. Keeley, Anthony S. Weiss,