Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5913336 | Blood Cells, Molecules, and Diseases | 2016 | 9 Pages |
Abstract
It demonstrates that AMD3100 and G-CSF may inhibit adhesion and migration abilities of leukemia cells with the bone marrow niche. Both of them inhibit the role of SDF-1/CXCR4 directly or indirectly. Thus inhibiting SDF-1/CXCR4 axis may be helpful to the treatment of refractory AML.
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Authors
Zhao-Hua Shen, Dong-Feng Zeng, Pei-Yan Kong, Ying-ying Ma, Xi Zhang,