Article ID Journal Published Year Pages File Type
5913336 Blood Cells, Molecules, and Diseases 2016 9 Pages PDF
Abstract
It demonstrates that AMD3100 and G-CSF may inhibit adhesion and migration abilities of leukemia cells with the bone marrow niche. Both of them inhibit the role of SDF-1/CXCR4 directly or indirectly. Thus inhibiting SDF-1/CXCR4 axis may be helpful to the treatment of refractory AML.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
Authors
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