| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5913348 | Blood Cells, Molecules, and Diseases | 2016 | 8 Pages |
Abstract
Our study showed that when a high erythropoietic stimulus occurs, hepcidin synthesis is mainly regulated by TSAT; however, when the erythropoiesis rate reaches a specific threshold, extramedullary hematopoiesis is triggered, and the control of hepcidin synthesis is switched to matriptase-2, thus inhibiting hepcidin synthesis.
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Authors
Sandra Ribeiro, PatrÃcia Garrido, João Fernandes, Susana Rocha, Petronila Rocha-Pereira, ElÃsio Costa, LuÃs Belo, Flávio Reis, Alice Santos-Silva,