| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5913586 | Blood Cells, Molecules, and Diseases | 2009 | 5 Pages |
Abstract
In this concise report, we describe the history and evolution of childhood acute leukemia studies in Brazil, and the application if key biomarkers for clinical trials and epidemiological studies over the past 8Â years. Highlights of each ongoing study are summarized. A Brazilian network integrating hospitals and scientific institutions from all country regions has been established. This organization is made possible through informatics and computer networking, and the standardization of pathological reviews including immunophenotyping and molecular characterization of childhood leukemias. The unique characteristics of the Brazilian population combined with a large clinical and epidemiologic framework for patient ascertainment has enabled large-scale epidemiological studies on childhood leukemia in Brazil.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Molecular Biology
Authors
Maria S. Pombo de Oliveira, Sergio Koifman, Gisele M. Vasconcelos, Mariana Emerenciano, Cristiane de Oliveira Novaes, Brazilian Collaborative Study Group of Infant Acute Leukemia Brazilian Collaborative Study Group of Infant Acute Leukemia,