Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5914543 | Journal of Structural Biology | 2012 | 7 Pages |
Abstract
Three dimensional (3D) electron microscopy techniques have become valuable tools for investigating cellular architecture and the processes that govern it. A vast amount of information is available in every 3D tomogram but the options for presenting this information in a clear and visually appealing way are limited. To address this, we developed D-CAT; a MatLab-application to accurately visualize the distribution of membrane proteins and/or membrane-bound structures. Presence (density) and distribution (clustering, depletion) are presented as color-coded areas on membranes. By using IMOD models both as input and output format, we ensure that the application fits within workflows common in the field of 3D electron microscopy.
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Authors
M.N. Lebbink, L.H.P. Hekking, W.J.C. Geerts, J.A. Post,