| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5915506 | Molecular and Biochemical Parasitology | 2013 | 9 Pages |
Abstract
⺠Identification and characterisation of Toxoplasma sphingolipid synthase (TgSLS). ⺠Demonstration of TgSLS inositol phosphorylceramide synthase activity. ⺠Identification of inositol phosphorylceramide in Toxoplasma extracts. ⺠Delineation of role of host sphingolipid biosynthesis in Toxoplasma proliferation. ⺠Host biosynthesis non-essential for proliferation, de novo synthesis could be key.
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Authors
Steven Pratt, Nilu K. Wansadhipathi-Kannangara, Catherine R. Bruce, John G. Mina, Hosam Shams-Eldin, Josefina Casas, Kentaro Hanada, Ralph T. Schwarz, Sabrina Sonda, Paul W. Denny,