Article ID Journal Published Year Pages File Type
5915529 Molecular and Biochemical Parasitology 2012 10 Pages PDF
Abstract
► Toxoplasma clone 13-20C2 is a conditional-lethal mitotic mutant. ► Temperature sensitivity was rescued by nuclear actin-related protein 4a. ► A single mutation in the helical domain of TgARP4a leads to mis-localization. ► While a lethal defect, daughter and spindle structures still form normally. ► Thus, division coordination likely requires both microtubule organizing centers.
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