Antimitotic herbicides bind to an unidentified site on malarial parasite tubulin and block development of liver-stage Plasmodium parasites

Binding of the herbicide amiprophosmethyl to Plasmodium falciparum tubulin was measured by fluoresence quenching (left) and the data used to compare affinities (right) to tubulins carrying alterations in possible herbicide binding sites.