Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5915613 | Molecular and Biochemical Parasitology | 2012 | 8 Pages |
Abstract
⺠Hco-LGC-38 is a novel nematode cys-loop GABA receptor. ⺠The channel is activated by both GABA and muscimol. ⺠The model of GABA docked into the Hco-LGC-38 binding-site shows similarity to models of other invertebrate GABA receptors. ⺠The Hco-LGC-38 channel is highly sensitive to picrotoxin and moderately sensitive to dieldrin and fipronil.
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Authors
Salma Z. Siddiqui, David D.R. Brown, Michael V. Accardi, Sean G. Forrester,