Article ID Journal Published Year Pages File Type
5915613 Molecular and Biochemical Parasitology 2012 8 Pages PDF
Abstract
► Hco-LGC-38 is a novel nematode cys-loop GABA receptor. ► The channel is activated by both GABA and muscimol. ► The model of GABA docked into the Hco-LGC-38 binding-site shows similarity to models of other invertebrate GABA receptors. ► The Hco-LGC-38 channel is highly sensitive to picrotoxin and moderately sensitive to dieldrin and fipronil.
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