| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5915632 | Molecular and Biochemical Parasitology | 2011 | 7 Pages |
Abstract
⺠Polynucleotide kinase/phosphatase gene of Plasmodium falciparum was cloned and expressed. ⺠3â²-Phosphatase activity was detected but 5â² kinase activity was not observed. ⺠The enzyme use only single-stranded substrates, and not double-stranded substrates. ⺠PfPNKP is more sensitive to sodium vanadate (Na3VO4) than human PNKP. ⺠Unlike human PNKP, PfPNKP is involved in single-strand breaks repair.
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Authors
Saranya Siribal, Michael Weinfeld, Feridoun Karimi-Busheri, J.N. Mark Glover, Nina K. Bernstein, Danny Aceytuno, Porntip Chavalitshewinkoon-Petmitr,