Article ID Journal Published Year Pages File Type
5915660 Molecular and Biochemical Parasitology 2011 9 Pages PDF
Abstract
► We compared the proteome of antimony resistant and sensitive Leishmania isolates. ► Antimony resistant isolates show modified expression of key metabolic pathways. ► Proteins involved in oxidative stress and intracellular survival were also modified. ► The identified parasite proteins could serve as surrogate markers for resistance.
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Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
Preview
Differential expression of proteins in antimony-susceptible and -resistant isolates of Leishmania donovani
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