| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5915723 | Molecular and Biochemical Parasitology | 2011 | 6 Pages |
Abstract
⺠Quinine in vivo effectiveness and in vitro activity are higher in Africa than in South East Asia. ⺠Bonafide in vivo resistance has been established in South East Asia, but not yet in Africa. ⺠Change in Phnhe gene is associated with reduced quinine in vitro activity. ⺠Pfhne in association with pfmdr1 gene could be used as markers of in vitro reduced quinine activity.
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Authors
John Okombo, Eric Ohuma, Stephane Picot, Alexis Nzila,