Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5916468 | Molecular Immunology | 2015 | 10 Pages |
Abstract
These results show that M. capsulatus Bath exhibit immunogenic properties in mammalian in vitro systems which diverge from that of E. coli Nissle 1917. This may provide clues to how M. capsulatus Bath influence the adaptive immune system in vivo. However, further in vivo experiments are required for a complete understanding of how this strain ameliorates intestinal inflammation in animal models.
Keywords
MNCLPSmonocyte-derived DCsDSSmoDCsPRRIBDiNOSTLRDendritic cell maturationinflammatory bowel diseasesImmunomodulationToll-like receptorDendritic cellsIntestinal epithelial cellsMononuclear cellsinducible nitric oxide synthaseDextran sulfate sodiumCytokinesMacrophage polarizationlipopolysaccharideIECspattern recognition receptors
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Authors
Trine Eker Christoffersen, Lene Therese Olsen Hult, Henriette Solberg, Anne Bakke, Katarzyna Kuczkowska, Eirin Huseby, Morten Jacobsen, Tor Lea, Charlotte Ramstad Kleiveland,