Structural consequences of aglycosylated IgG Fc variants evolved for FcÎ³RI binding

Article ID	Journal	Published Year	Pages	File Type
5916654	Molecular Immunology	2015	7 Pages	PDF

Keywords

ADCP SAXS smFRET ALEX FcγR ADCC PDB CDC PBS IgG antibody-dependent cell-mediated cytotoxicity Förster resonance energy transfer FRET immunoglobulin G Effector function Single-molecule analysis ELISA Enzyme-linked immunosorbent assay TCEP complement-dependent cytotoxicity Fab Phosphate buffered saline fragment antigen binding fragment crystallizable Antibody engineering Small-angle X-ray scattering Protein Data Bank Fc gamma receptor single-molecule FRET

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology

Structural consequences of aglycosylated IgG Fc variants evolved for FcÎ³RI binding

Authors

Man-Seok Ju, Jung-Hyun Na, Yeon Gyu Yu, Jae-Yeol Kim, Cherlhyun Jeong, Sang Taek Jung,