| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5916908 | Molecular Immunology | 2014 | 11 Pages |
Abstract
The inhalation of aerosolized anti-IL-1β IgY inhibits pathological responses in the pulmonary tissues of guinea pigs with allergic asthma. The inhibitory activity may be due to the decrease in the numbers of eosinophils and neutrophils and the reduced levels of inflammatory cytokines and IgE in the PB and BALF.
Keywords
IL-1RAanti-IgE antibodyT helper type 2sTNFRIL-13Th2IL-8IL-1βOVAIL-4AHRIgETGF-β1IgYAllergic asthmaIL-1 receptor antagonistOvalbuminOmalizumab IgE, immunoglobulin Einterleukin-4Interleukin-8Interleukin-13interleukin-1betaInterleukin-1βInfliximabBALFTransforming growth factor-beta 1tumor necrosis factor-alphaPeripheral bloodGuinea pigsSRAWCytokinesTNF-αBronchoalveolar lavage fluidspecific airway resistancehematoxylin-eosinAirway hyperresponsiveness
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Authors
Hu Wei-xu, Xiang Qin, Wen Zhu, Chen Yuan-yi, Zeng Li-feng, Liu Zhi-yong, He Dan, Wu Xiao-mu, Hu Guo-zhu,