Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5916998 | Molecular Immunology | 2013 | 8 Pages |
Abstract
⺠Recombinant grass carp IL-10 (rgcIL-10) has been purified. ⺠Both rgcIL-10 and TGF-β1 induced the cell activation of peripheral blood lymphocytes. ⺠Removal of endogenous IL-10 could abolish TGF-β1-induced cell activity. ⺠TGF-β1 enhanced gcIL-10 mRNA expression and protein secretion in the same cell model. ⺠TGF-β1 may function through its effect on IL-10 production in fish immunity.
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Authors
He Wei, Mu Yang, Taiqiang Zhao, Xinyan Wang, Hong Zhou,