Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917000 | Molecular Immunology | 2013 | 10 Pages |
Abstract
⺠DIM inhibited Th2 responses in naive T cells via AhR signaling. ⺠DIM mediated reciprocal regulation of Th17 and Treg in naive T cells is AhR dependent. ⺠DIM attenuated oxazolone-induced colitis via regulating mucosal T cell responses.
Keywords
T-helperIFN-γEAETCDDFICZERαIBDTNBSi3CmAbsDAI6-formylindolo[3,2-b]carbazoleshRNACCK-8AHRTGF-β1DSSTregs2,3,7,8-Tetrachlorodibenzo-p-dioxin2,4,6-trinitrobenzenesulfonic acid3,3′-diindolylmethaneMPOH&EIndole-3-carbinolMOIshort hairpin RNAexperimental autoimmune encephalomyelitisDIMperiodic acid-Schiffinterferon-γinterleukinInflammatory bowel diseaseTransforming growth factor-β1T-helper cellT regulatory cellsRegulatory T cellsdextran sodium sulfatedisease activity indexcell counting kit-8myeloperoxidasePAShematoxylin–eosinMonoclonal antibodiesmultiplicity of infectionUlcerative colitisaryl hydrocarbon receptorEstrogen receptor α
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Authors
Zhen Huang, Yucui Jiang, Yang Yang, Juan Shao, Xulun Sun, Jiangning Chen, Lei Dong, Junfeng Zhang,