Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917005 | Molecular Immunology | 2013 | 11 Pages |
Abstract
⺠Multivalent antigen presentation improves delivery through DC-SIGN. ⺠16-32 glycan units are the optimal multivalency for DC-SIGN targeting. ⺠DC-SIGN mediated uptake results in robust CD4 and CD8T cell responses.
Keywords
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Authors
Juan J. GarcÃa-Vallejo, Martino Ambrosini, Annemieke Overbeek, Wilhelmina E. van Riel, Karien Bloem, Wendy W.J. Unger, Fabrizio Chiodo, Jan G. Bolscher, Kamran Nazmi, Hakan Kalay, Yvette van Kooyk,