Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917010 | Molecular Immunology | 2013 | 7 Pages |
Abstract
⺠S100A8 reduces PMN inflammation and oxidative damage caused by LPS. ⺠Activating PAR2 enhances the protective effect of S100A8 in endotoxemic mice. ⺠S100A8 and PAR2 synergize and significantly reduce the mortality caused by LPS.
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Authors
Ying Sun, Yu Lu, Christopher G. Engeland, Sara C. Gordon, Herve Y. Sroussi,