| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5917013 | Molecular Immunology | 2013 | 4 Pages |
Abstract
⺠Of the 20 amino acid positions of HLA-B resulted associated with LTNP or FP, 8 interacts with NK receptors. ⺠Bw4 epitope resulted significantly associated with delayed disease progression. ⺠Amino acid polymorphism Val 194 located on α3-domain of HLA-B associates with LTNP ⺠The amino acid change Val to Ile at position 194 modifies the interaction amino acid residues interaction between HLA-B molecule and LIR1 receptor.
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Authors
Alba Grifoni, Carla Montesano, Paolo Palma, Alfredo Salerno, Vittorio Colizzi, Massimo Amicosante,