Article ID Journal Published Year Pages File Type
5917292 Molecular Immunology 2013 4 Pages PDF
Abstract
► A subset of MHC-I peptides is generated by alternative processing routes, independent of proteasome and TAP. ► A broad and unique peptide repertoire is presented on TAP-deficient cells. ► Several processing pathways deliver these TAP-independent peptides. ► We are unraveling a novel route that depends on membrane-associated proteolysis and macro-authophagy.
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Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
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